快樂小藥師 Im pharmacist nichts glücklich

Safety Announcement

Question

What is the risk to the unborn baby of proton pump inhibitor therapy during pregnancy? Should these drugs be avoided altogether in pregnant women?

孕婦最擔心的，就是小孩營養不夠，會讓發育不好，但是如果補充太多，又怕會有傷害，最有名的例子，就是維他命A的補充。

The US Food and Drug Administration (FDA) announced today that it has approved a new, once-a-day drug to treat chronic obstructive pulmonary disease (COPD), even though an agency advisory panel of outside experts had opposed it on safety and efficacy grounds.

美國食品暨藥物管理局（FDA）今天宣布，將把500多種可能有安全疑慮的感冒、咳嗽和過敏處方藥下架。

大家都知道，孕婦要補充葉酸，但是，到底要補充多少呢？

 根據臨床內分泌與新陳代謝雜誌Journal of Clinical Endocrinology & Metabolism在網上公佈的一項研究，一個新的生物標記可能可以早期診斷異位妊娠。

去年一整年來，對於女性健康最熱門的文章整理

Information sourced from Journal Watch:

陰道片劑：最為大家熟悉的，就是mycostatin和metronidazole，另外一個比較特別的，是Talsutin

通常陰道片劑都是用來治療感染用的，但是有時候卻會聽到病患抱怨沒用還好，用了更難受，到底發生什麼事情？

沒錯，本人就是很愛吃牛排。

這次剛好有機會走到西門町的另外一頭，所以就在巷子裡面發現這家餐廳：

千呼萬換，總算是出現了，而且就像謠言所稱，帶著LPK出現，新的名稱是：thunderbolt

以往對於百貨公司裡面的餐廳總是有一種很昂貴的感覺，不過這次在統一裡面，卻發現這一家餐廳：saizeriya

Haemophilia A and B are X-linked bleeding disorders caused by an inherited deficiency of factor VIII or factor IX, respectively. Of the approximately 1 per 5000–10 000 male births affected by haemophilia, 80% are deficient in factor VIII and 20% are deficient in factor IX. The National Foundation of Haemophilia estimates the worldwide incidence to be near 400 000 people,[¹] most of whom do not have ready access to medical care. The clinical phenotype mainly correlates with the level of endogenous factor, with the most severe phenotype presenting with factor levels below 1% of normal. As a disorder of secondary haemostasis, haemophilia is characterized by spontaneous and provoked joint, muscle, gastrointestinal and CNS bleeding, leading to major morbidity and even mortality if left untreated or under-treated. This article aims to review the current treatment options for patients with congenital haemophilia A and B, including clotting factor repletion, inhibitor reduction and adjuvant treatment. Because the treatment of haemophilia is advancing rapidly, the future direction of haemophilia treatment is reviewed.

BACKGROUND

Retinopathy of prematurity is a leading cause of childhood blindness worldwide. Peripheral retinal ablation with conventional (confluent) laser therapy is destructive, causes complications, and does not prevent all vision loss, especially in cases of retinopathy of prematurity affecting zone I of the eye. Case series in which patients were treated with vascular endothelial growth factor inhibitors suggest that these agents may be useful in treating retinopathy of prematurity.

Hello. This is Jeffrey Burns from the University of Pennsylvania School of Medicine in Philadelphia. I am Editor-in-Chief of Medscape Nephrology.

Clinicians should not use injectable terbutaline to prevent preterm labor or treat it beyond 48 to 72 hours because of the risk for maternal heart problems and death, the US Food and Drug Administration (FDA) announced today.

先給大家看一下台灣的新聞：

This Journal feature begins with a case vignette that includes a therapeutic recommendation. A discussion of the clinical problem and the mechanism of benefit of this form of therapy follows. Major clinical studies, the clinical use of this therapy, and potential adverse effects are reviewed. Relevant formal guidelines, if they exist, are presented. The article ends with the author's clinical recommendations.

第一次聽到這東西時，是在學新秘時聽到的，我想說安瓶？這是啥？

結果前輩拿了一個我很熟悉的東西出來，我才明白，

原來，就是安瓿（ampoule）

BACKGROUND

Prenatal repair of myelomeningocele, the most common form of spina bifida, may result in better neurologic function than repair deferred until after delivery. We compared outcomes of in utero repair with standard postnatal repair.

Purpose Induction immunosuppressive therapies for patients undergoing renal transplantation are reviewed.

最近看到一個廣告，我百思不得其解：

請問，那你平常都出生入死，拋頭顱，灑熱血嗎？不然流失一半有很多嗎？

因為廠商都沒有提供可靠文獻來源，唯一有講到的，只有衛生署證實療效而：

Purpose: The stability of extemporaneously prepared acetylcysteine 1% and 10% solutions for treatment of meconium ileus was evaluated.

Purpose: Drug therapies for patients with acute heart failure syndromes (AHFS) are reviewed, including clinical practice guideline recommendations for the treatment of hospitalized patients with heart failure (HF).