What Is Food Allergy?

Food allergy is an immunoglobulin (Ig)E- or non-IgE-mediated immune response to food protein. This column will focus on IgE-mediated food allergy represented by immediate hypersensitivity (Gell-Coombs Type I), which can include anaphylaxis and can be life-threatening. Non-IgE-mediated reactions are thought to be cell mediated (allergic eosinophilic esophagitis/gastroenteritis, food protein-induced proctocolitis, food protein-induced enterocolitis syndrome, food protein-induced enteropathy [including celiac disease], and food-induced pulmonary hemosiderosis).

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