Cinryze(C1 inhibitor (human))

Mechanism of Action
supplies C1 inhibitor, suppresses contact system activation by inactivating plasma kallikrein and factor XIIa, may decr. vascular permeability by preventing bradykinin generation


目前適應症:

CINRYZE is a C1 inhibitor indicated for routine prophylaxis against angioedema attacks in adolescent and adult patients with Hereditary Angioedema (HAE).

Cinryze C1抑制劑療法成功治療所有型態急性遺傳性血管腫(H.A.E.)。罹患H.A.E.的病人以Cinryze治療平均30分鐘以後病症獲得改善


DOSAGE FORMS AND STRENGTHS

Approximately 500 Units (lyophilized) in a 8 mL vial.


Patient Education - English

Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. 

Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. 

The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.


相關資料可以參考這邊:

Hereditary Angioedema n engl j med 359;10 www.nejm.org september 4, 2008


 

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