US Pharm. 2013;38(12):HS2-HS5.
ABSTRACT: The carbapenem-resistant Enterobacteriaceae (CRE) comprise resistant gram-negative bacteria with limited treatment options and a high mortality rate. CRE infection is a growing threat, especially in the healthcare setting. The Clinical and Laboratory Standards Institute has defined laboratory indicators to determine the presence of CRE. Combination regimens including polymyxins, tigecycline, and aminoglycosides have been reported with limited success. Recommended prevention strategies are delineated by the CDC and should be implemented to thwart transmission of CRE. Pharmacists can optimize the management of patients with CRE infections by understanding the appropriate treatment and prevention measures for this emerging healthcare problem.
For several decades, clinicians have relied on the use of carbapenem antimicrobials to treat infections caused by resistant organisms. The development of resistance to broad-spectrum antimicrobials and the prevalence of carbapenem-resistant Enterobacteriaceae (CRE) in the United States have increased over the past 20 years.
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US Pharm. 2013;38(12):HS14-HS20.
ABSTRACT: Appendicitis is an inflammation of an obstructed appendix that may become infected, gangrenous, and perforated. Classically, it presents as abdominal pain that is often accompanied by nausea and vomiting. Appendicitis is the most common cause of abdominal surgery in children, with the highest incidence during the second decade of life. A ruptured appendix, however, is more common in younger children. There is no one diagnostic measure that is specific for appendicitis, and in many cases, a wrong diagnosis may be made, particularly in children. The condition can be managed with antibiotics as well as an appendectomy, if necessary.
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US Pharm. 2013;38(11):HS3-HS6.
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US Pharm. 2013;38(10):HS13-HS20.
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US Pharm. 2013;38(9):23-26.
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US Pharm. 2013;38(9):HS12-HS16.
ABSTRACT: Many different types of infections can occur during pregnancy. Common infections include sexually transmitted diseases (syphilis, gonorrhea, chlamydia, herpes), urinary tract infections, group B streptococcal disease, listeriosis, and toxoplasmosis. A number of antimicrobial therapy regimens may be used during pregnancy. Pharmacists are in a key position to improve outcomes for pregnant women with any of these infections through recommendations for antimicrobial therapy, monitoring for adverse effects, prevention of drug interactions, and counseling on adherence. Counseling points for pregnant women include appropriate preventive measures, such as lifestyle modifications.
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US Pharm. 2013;38(9):43-46.
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US Pharm. 2013;38(8):HS4-HS8.
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US Pharm. 2013;8(38):22-26.
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