Topical-steroids-655x353.jpg

Class I 最強;VII最弱

更新到2019

Comparison of representative topical corticosteroid preparations (classified according to the US system)

Potency group*

Corticosteroid

Vehicle type/form

Trade names
(United States)

Available strength(s), percent
(except as noted)

Super-high potency
(group 1)

Betamethasone dipropionate, augmented

Ointment, optimized

Diprolene

0.05

Lotion

Diprolene

0.05

Gel

Diprolene

0.05

Clobetasol propionate

Ointment

Temovate

0.05

Cream

Temovate

0.05

Cream, emollient base

Temovate E

0.05

Gel

Temovate

0.05

Lotion

Clobex

0.05

Foam aerosol

Olux-E

0.05

Foam aerosol (scalp)

Olux

0.05

Shampoo

Clobex

0.05

Solution (scalp)

Temovate, Cormax

0.05

Spray aerosol

Clobex

0.05

Diflucortolone valerate (not available in United States)

Ointment, oily cream

Nerisone Forte (United Kingdom, others)

0.3

Fluocinonide

Cream

Vanos

0.1

Flurandrenolide

Tape (roll)

Cordran

4 mcg/cm2

Halobetasol propionate

Ointment

Ultravate

0.05

Cream

Ultravate

0.05

Lotion

Ultravate

0.05

High potency
(group 2)

Amcinonide

Ointment

Cyclocort, Amcort

0.1

Betamethasone dipropionate

Ointment

Diprosone

0.05

Cream, augmented formulation (AF)

Diprolene AF

0.05

Clobetasol propionate

Cream

Impoyz

0.025

Desoximetasone

Ointment

Topicort

0.25

Cream

Topicort

0.25

Spray

Topicort

0.25

Gel

Topicort

0.05

Diflorasone diacetate

Ointment

ApexiCon, Florone

0.05

Cream, emollient

ApexiCon E

0.05

Fluocinonide

Ointment

Lidex

0.05

Gel

Lidex

0.05

Cream anhydrous

Lidex

0.05

Solution

Lidex

0.05

Halcinonide

Ointment

Halog

0.1

Cream

Halog

0.1

Halobetasol propionate

Lotion

Bryhali

0.01

High potency
(group 3)

Amcinonide

Cream

Cyclocort, Amcort

0.1

Lotion

Amcort

0.1

Betamethasone dipropionate

Cream, hydrophilic emollient

Diprosone

0.05

Betamethasone valerate

Ointment

Valisone

0.1

Foam

Luxiq

0.12

Desoximetasone

Cream

Topicort LP

0.05

Diflorasone diacetate

Cream

Florone

0.05

Diflucortolone valerate (not available in United States)

Cream, oily cream, ointment

Nerisone (Canada, United Kingdom, others)

0.1

Fluocinonide

Cream aqueous emollient

Lidex-E

0.05

Fluticasone propionate

Ointment

Cutivate

0.005

Mometasone furoate

Ointment

Elocon

0.1

Triamcinolone acetonide

Ointment

Kenalog

0.5

Cream

Triderm, Aristocort HP

0.5

Medium potency
(group 4)

Betamethasone dipropionate

Spray

Sernivo

0.05

Clocortolone pivalate

Cream

Cloderm

0.1

Fluocinolone acetonide

Ointment

Synalar

0.025

Flurandrenolide

Ointment

Cordran

0.05

Hydrocortisone valerate

Ointment

Westcort

0.2

Mometasone furoate

Cream

Elocon

0.1

Lotion

Elocon

0.1

Solution

Elocon

0.1

Triamcinolone acetonide

Cream

Kenalog

0.1

Ointment

Kenalog

0.1

Aerosol spray

Kenalog

0.2 mg per 2 second spray

Lower-mid potency
(group 5)

Betamethasone dipropionate

Lotion

Diprosone

0.05

Betamethasone valerate

Cream

Beta-Val, Valisone

0.1

Desonide

Ointment

DesOwen, Tridesilon

0.05

Gel

Desonate

0.05

Fluocinolone acetonide

Cream

Synalar

0.025

Flurandrenolide

Cream

Cordran

0.05

Lotion

Cordran

0.05

Fluticasone propionate

Cream

Cutivate

0.05

Lotion

Cutivate

0.05

Hydrocortisone butyrate

Ointment

Locoid

0.1

Cream

Locoid, Locoid Lipocream

0.1

Lotion, spray

Cortizone 10 maximum

0.1

Lotion

Locoid

0.1

Solution

Locoid

0.1

Hydrocortisone probutate

Cream

Pandel

0.1

Hydrocortisone valerate

Cream

Westcort

0.2

Prednicarbate

Cream, emollient

Dermatop

0.1

Ointment

Dermatop

0.1

Triamcinolone acetonide

Lotion

Kenalog

0.1

Ointment

Kenalog

0.025

Low potency
(group 6)

Alclometasone dipropionate

Ointment

Aclovate

0.05

Cream

Aclovate

0.05

Betamethasone valerate

Lotion

Beta-Val, Valisone

0.1

Desonide

Cream

DesOwen, Tridesilon

0.05

Lotion

DesOwen, LoKara

0.05

Foam

Verdeso

0.05

Fluocinolone acetonide

Cream

Synalar

0.01

Solution

Synalar

0.01

Shampoo

Capex

0.01

Oil (scalp)Δ

Derma-Smoothe/FS Scalp

0.01

Oil (body)Δ

Derma-Smoothe/FS Body

0.01

Triamcinolone acetonide

Cream

Kenalog, Aristocort

0.025

Lotion

Kenalog

0.025

Least potent
(group 7)

Hydrocortisone (base, ≥2%)

Ointment

Hytone

2.5

Cream

Hytone, Nutracort

2.5

Lotion

Hytone, Ala Scalp, Scalacort

2.5 or 2

Solution

Texacort

2.5

Hydrocortisone (base, <2%)

Ointment

Cortaid, Hytone, Nutracort

1

Cream

Cortaid, Hytone, Synacort

1

Lotion

Aquanil HC, Sarnol-HC, Cortizone 10

1

Spray

Cortaid

1

Solution

Cortaid, Noble, Scalp relief

1

Ointment

Cortaid

0.5

Cream

Cortaid

0.5

Hydrocortisone acetate with pramoxine 1% combination

Ointment

Pramosone

1 or 2.5

Cream

Pramosone, Analpram-HC

1 or 2.5

Lotion

Pramosone, Analpram-HC

1 or 2.5

Aerosol foam

Epifoam

1

 

US: United States.
* Listed by potency according to the US classification system: group 1 is the most potent, group 7 is the least potent. Other countries use a different classification system with only four or five groups.
¶ Inactive United States trade name for specific product; brand may be available outside United States.
Δ 48% refined peanut oil.

Data from: 

1.      Lexicomp Online. Copyright © 1978-2019 Lexicomp, Inc. All Rights Reserved.

2.      Tadicherla S, Ross K, Shenefelt D. Topical corticosteroids in dermatology. Journal of Drugs in Dermatology 2009; 12:1093.

3.      U.S. Food & Drug Administration Approved Drug Products with Therapeutic Equivalence (Orange Book). Available at: https://www.accessdata.fda.gov/scripts/cder/ob/default.cfm (Accessed on June 18, 2017).

 

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