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DRUG

GROUP

ASPIRATE

And instill

steroids⁰⁰¹

'SPREAD’ AND DILUTE

LOCALISE AND NEUTRALISE

SPECIFIC MANAGEMENT

ADDITIONAL

INFORMATION

Thiotepa

1

Y

Y

Infiltrate the site with hyaluronidase.a Apply heat and compression.2 g

Topotecan

4

Y

Y

Infiltrate with sodium bicarbonate into the area, followed by heat (i.e. warm compression.g)

Extravasation is rare

See j

Treosulphan

5

Y

Y

Infiltrate with sodium bicarbonate into the area, followed by heat (i.e. warm compression.g)

Extravasation is rare

See j Although surgical excision e is sometimes required to prevent serious damage

Vinblastine

5

Y

Y

Infiltrate the area with hyaluronidase,a as 0.2 ml injections, over and around the circumference of the affected area. Apply heat and compression.5 g

Vincristine

5

Y

Y

Infiltrate the area with hyaluronidase,^a as 0.2 ml injections, over and around the circumference of the affected area. Apply heat and compression.5 g

Vindesine

5

Y

Y

Infiltrate the area with hyaluronidase,a as 0.2 ml injections, over and around the circumference of the affected area. Apply heat and compression.5 g

Vinorelbine

5

Y

Y

Infiltrate the area with hyaluronidase,^a as 0.2 ml injections, over and around the circumference of the affected area. Apply heat and compression.5 g