並不是每一個國家羅氏都有在提供tamiflu的懸液劑，所以最快速的方式，就是拆膠囊了。
FDA提供的建議：
Commercially manufactured Tamiflu for Oral Suspension (12 mg/mL) is the preferred product for pediatric and adult patients who have difficulty swallowing capsules or where lower doses are needed. In the event that Tamiflu for Oral Suspension is not available, pharmacists may compound a suspension (15 mg/mL) from Tamiflu (oseltamivir phosphate) Capsules 75 mg using Cherry Syrup (Humco) or Ora-Sweet Sugar-Free (SF; Paddock Laboratories). Other vehicles have not been studied. This compounded suspension should not be used for convenience or when the FDA-approved Tamiflu for Oral Suspension is available.
The approved compounding procedure is included in the professional prescribing information and results in a 15 mg/mL suspension. Healthcare providers should note that the compounded suspension is a different concentration compared to commercially available Tamiflu for Oral Suspension, which has a concentration of 12 mg/mL. Pharmacists and health care providers should ensure that an appropriate dispensing device (i.e., one that measures volume in mL) is provided with the compounded suspension of Tamiflu.
The following tables provide the volume of compounded suspension (15 mg/mL) made from Tamiflu Capsules needed for a full treatment course based on the patient’s weight, and the dosing chart for pharmacy-compounded Tamiflu suspension.
Total Volume of Suspension Needed for Correct Dosing
| Body Weight (kg) |
Body Weight (lbs) |
Total Volume to Compound per patient (mL) |
| < 15 kg |
< 33 lbs |
30 mL |
| 16 to 23 kg |
34 to 51 lbs |
40 mL |
| 24 to 40 kg |
52 to 88 lbs |
50 mL |
| > 41 kg |
& > 89 lbs |
60 mL |
Dosing Chart for Pharmacy-compounded Tamilfu
|
Body Weight (kg) |
Body Weight (lbs) |
Dose (mg) |
Volume per Dose |
Treatment Dose Required (for 5 days) |
Prophylaxis Dose Required |
|
< 15 kg |
< 33 lbs |
30 mg |
2 mL |
2 mL twice daily |
2 mL once daily |
|
16 to 23 kg |
34 to 51 lbs |
45 mg |
3 mL |
3 mL twice daily |
3 mL once daily |
|
24 to 40 kg |
52 to 88 lbs |
60 mg |
4 mL |
4 mL twice daily |
4 mL once daily |
|
> 41 kg |
> 89 lbs |
75 mg |
5 mL |
5 mL twice daily |
5 mL once daily |
Healthcare professionals and consumers can access complete compounding directions and other information on emergency compounding of an oral suspension from Tamiflu Capsules in the Tamiflu package insert at: http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=11065
其他關於Tamiflu的文章：
Risk of Confusion in Dosing Tamiflu Oral Suspension in Children
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