Classification table of vesicants
Cytotoxic and non-cytotoxic drugs with potential for tissue damage
|
Cytotoxic drugs |
Hyperosmolar agents |
Potentially damaging acid and alkaline agents |
|
*Actinomycin D * Amsacrine * Carmustine * Dacarbazine *Daunorubicin *Doxorubicin *Epirubicin *Idarubicin *Mitomycin C Paclitaxel *Streptozocin Treosulfan Ψ Vinblastine Ψ Vincristine Ψ Vindesine Ψ Vinorelbine
|
Ψ Calcium chloride Ψ Calcium gluconate 10% Hypertonic glucose (10% or >) Hypertonic sodium chloride (10% or >) Magnesium sulphate 20% Mannitol 10% & 20% Ψ Parenteral nutrition Sodium bicarbonate Ψ X-ray Contrast media Vascular regulators Adrenaline Dobutamine Dopamine Noradrenaline (Norepinephrine) Prostaglandins Vasopressin |
Aciclovir Ψ Aminophylline Amiodarone Amphotericin B Co-trimoxazole Diazepam Erythromycin Foscarnet sodium Ganciclovir GTN infusion Methylene Blue Ψ Phenytoin Vancomycin |
*BLUE = apply cold compress to affected area for 20 minutes to localise and neutralise 4x daily for 24-48 hours.
ψ RED = apply warm compress to affected area for 20 minutes to spread and dilute 4x daily for 24-48 hours
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