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Drug Category

Drug

Side Effect

Beta-blockers

Befunolol

Betaxolol

Carteolol

Levobunolol

Metipranolol

Timolol

Mepindolol

bronchospasm, shortness of breath fatigue, confusion, depression,

impotence, hair loss, heart failure,bradycardia. Timolol has also been found to decrease HDL levels and

adversely effect the total

cholesterol:HDL ratio in women 60 years and older

Non-selective Adrenergic

Agonists

epinephrine, dipivefrin

high incidence of allergic or toxic

reactions

α2-Selective Adrenergic

Agonists

apraclonidide

brimonidine

Clonidine

Dipivefrine

high rate of allergic reactions,

tachyphylaxis dry mouth but less likely to cause allergic reactions

Cholinergic Agonists

muscarinic

Aceclidine

carbachol

pilocarpine

detached retina, GI disturbances,

headache, frequent urination hypertension, tachycardia, bronchial spasm

Carbonic Anhydrase

Inhibitors

(oral, IV, topical)

acetazolamide,

Brinzolamide

methazolamide,

dichlorphenamide,

ethoxzolamine

dorzolamide

fatigue, anorexia, depression,

paresthesias, electrolyte abnormalities,kidney stones, blood dyscrasias

topical so does not have the side

effects of the others

Prostaglandin Analog(2α)

Latanoprost

Bimatoprost

Tafluprost

Travoprost

Unoprostone

increased pigmentation of the iris;worsening of uveitis

selective prostaglandin E2 receptor 2 agonist

Omidenepag isopropyl

結膜充血、角膜肥厚、黃斑水腫、眼部疼痛、畏光

acetylcholinesterase inhibitors

Demecarium

Ecothiopate

Fluostigmine

Neostigmine

Physostigmine

Paraoxon

rho kinase inhibitor

Netarsudil

eye pain

lid redness

discoloration of the eye

其他

Dapiprazole

Guanethidine

Ripasudil