比較Prozac、seroxate與Zoloft
FLUOXETINE HYDROCHLORIDE | PAROXETINE HYDROCHLORIDE | SERTRALINE HYDROCHLORIDE | |
Details in DRUGDEX® | FLUOXETINE | PAROXETINE | SERTRALINE |
商品名 |
See Complete Tradename Listing |
See Complete Tradename Listing |
See Complete Tradename Listing |
分類 |
|
|
|
劑量 | 憂鬱症:5-20 mg/day in the morning; max. 80 mg/day. 強迫症: Initially 20 mg/day; maintenance 20-60 mg/day 早上及晚上 max. 80 mg/day. 暴食症:60 mg/day每天早上 | PO, in the morning 焦慮症: 20 mg/day. 憂鬱症:Initially, 20 mg/day; increased by 10 mg/day q7d; max. 50 mg/day. 強迫症: Initially, 20 mg/day; increased by 10 mg/day q7d; maintenance, 40 mg/day; max. 60 mg/day. 創傷後壓力症候群: Initially, 10 mg/day; increased by 10 mg/day q7d; maintenance, 40 mg/day; max. 60 mg/day. | PO. 憂鬱症及強迫症: Initially, 50 mg qd; max. 200 mg/day. 創傷後壓力症候群:Initially, 25 mg qd; max. 200 mg/day. |
半衰期 | 2~3天 | 16~24小時 | 26小時 |
代謝 | 2D6、3A4、2C | 2D6 | 2D6、3A4、2C |
13% | 11% | 14% ref:apa Am j psychiatry1996 | |
適應症 | 抑鬱症、暴食症、強迫症。 | 各種類型鬱症及鬱症伴隨焦慮症之症狀治療及預防復發、強迫症之症狀治療、恐慌症之症狀治療及預防復發、社交畏懼症(社交焦慮症)之治療、泛焦慮症之症狀治療及預防復發(GAD)、創傷後壓力症候群之治療(PTSD)。 | 鬱症、強迫症、恐慌症、創傷後壓力症候群、社交恐懼症。 |
單位價格 | 19.2 | 44.5 | 47 |
日價格 | 19.2~76.8 | 44.5~133.5 | 47~188 |
健保規定 | 1.2.1. 選擇性血清促進素再吸收抑制劑(SSRI)及血清促進素及正腎上腺素再吸收抑制劑(SNRI)抗憂鬱劑」(fluvoxamine maleate;fluoxetine; paroxetine;sertraline;venlafaxine HCl、milnacipran等製劑)之給付規定:(88/12/1、89/10/1、91/5/1、92/6/1、93/5/1) 使用時須符合衛生主管機關核准之適應症,病歷應詳細註明診斷依據及使用理由。 |
全站熱搜
留言列表