Baxter International Inc. today announced that the U.S. Food and Drug Administration (FDA) has approved ADVATE [Antihemophilic Factor (Recombinant) Plasma/Albumin Free Method] for routine prophylaxis to prevent or reduce the frequency of bleeding episodes in patients with hemophilia A. ADVATE is the only antihemophilic factor approved in the United States for prophylactic use in both adults and children.
上次跟各位提過可能影響性反應的藥物分類 Classes of medication that may affect sexual response
現在來介紹哪些藥物是用來治療因為服用抗憂鬱繼而引起的性功能障礙
服用部分藥物可能會改變性的反應，例如性慾低落，或是異常勃起，百憂解(fluoxetine)就是其中一個例子
FDA核准 Jakafi 治療骨髓纖維化的藥物
The U.S. Food and Drug Administration today approved Jakafi (ruxolitinib), the first drug approved to specifically treat patients with the bone marrow disease myelofibrosis.
使用diazepam或lorazepam來治療酒精中毒比較表
Bazedoxifene (Conbriza®, Viviant®) is the first third-generation selective estrogen receptor modulator (SERM) and it is approved for the treatment of postmenopausal osteoporosis in the EU and Japan. Bazedoxifene contains an indole-based core binding domain that binds with high affinity to estrogen receptors and exhibits favourable effects on bone and lipid profiles, with no clinically relevant endometrial or breast stimulation. Oral bazedoxifene once daily reduced the incidence of new vertebral fractures in patients with postmenopausal osteoporosis in a large, well designed trial of 3 years' duration; both bazedoxifene and raloxifene were significantly more effective than placebo. Neither bazedoxifene nor raloxifene reduced the incidence of nonvertebral fractures in the overall study population; however, bazedoxifene, but not raloxifene, reduced the rate of nonvertebral fractures in high-risk patients. Moreover, data from patients who continued to receive the drug during a 2-year extension phase of this trial indicate that bazedoxifene continues to provide protection against new vertebral fractures for up to 5 years. Bazedoxifene also increases bone mineral density and reduces the levels of bone turnover markers. Bazedoxifene was generally well tolerated and did not detrimentally affect the reproductive tract or breast tissue in clinical trials, thereby demonstrating a favourable risk-benefit profile. A pharmacoeconomic analysis conducted from an EU perspective predicted bazedoxifene to be cost effective in some EU countries. Therefore, bazedoxifene presents another useful option for the treatment of postmenopausal osteoporosis, especially in those at high risk for osteoporotic fracture.
By Dr Ananya Mandal, MD
The U.S. Centers for Disease Control and Prevention (CDC) has released new guidelines on treating so-called “latent” tuberculosis (TB) infection in the United States. They suggest the course of the therapy from about 9 months could be shortened to 3 months.
除了本身的疾病造成以外，下面表格是藥物引起的食道逆流
成骨不全症（Osteogenesis Imperfecta）指的是一種因先天遺傳性缺陷而引起第一型膠原纖維病變，造成骨骼強度耐受力變差而容易脆弱骨折的疾病。男性女性受侵犯的機率大約相同，統計上每二萬個生產會有一個，成骨不全症根據遺傳基因或骨骼脆度及骨骼系統外的表徵一般分成四型（ Sillence classification I-IV），另外比較細的分類會分到八型。
Rheumatoid arthritis is a common autoimmune disease that is associated with progressive disability, systemic complications, early death, and socioeconomic costs.1 The cause of rheumatoid arthritis is unknown, and the prognosis is guarded. However, advances in understanding the pathogenesis of the disease have fostered the development of new therapeutics, with improved outcomes. The current treatment strategy, which reflects this progress, is to initiate aggressive therapy soon after diagnosis and to escalate the therapy, guided by an assessment of disease activity, in pursuit of clinical remission.
The anti–human epidermal growth factor receptor 2 (HER2) humanized monoclonal antibody trastuzumab improves the outcome in patients with HER2-positive metastatic breast cancer. However, most cases of advanced disease eventually progress. Pertuzumab, an anti-HER2 humanized monoclonal antibody that inhibits receptor dimerization, has a mechanism of action that is complementary to that of trastuzumab, and combination therapy with the two antibodies has shown promising activity and an acceptable safety profile in phase 2 studies involving patients with HER2-positive breast cancer.
根據一篇新研究，對於患有慢性腎臟病(CKD)的糖尿病患，糖化血色素(HbA1c))目標介於7%-9%者，則副作用風險降低，若數據超出或低於前述範圍時，風險則會增加。
In some ways, each person with multiple sclerosis lives with a different illness. Although nerve damage is always involved, the pattern is unique for each individual who has MS.
Although individual experiences with MS vary widely, doctors and researchers have identified several major types of MS. The categories are important. That's because they help predict disease severity -- and response to treatment.
Study Finds Higher Arsenic Levels in Pregnant Women Who Eat Rice; Researchers Say That Exposure Could Harm Developing Baby
WebMD Health News
Reviewed by Louise Chang, MD
有位47歲的治療師Julie Rudiger談到健身方法時表示，她已經厭倦了重複一個動作或是踩健身腳踏車，她在2009年時，因為想要拉肌肉並強化心靈而選擇了瑜伽，最後，這成了她的首選運動。
太極拳屬於一系列緩慢、精心安排的武術動作，彼拉提斯是能增強核心力量的無傷害性運動，瑜伽則是有益心/身健康的運動。她認為很多人低估了瑜伽對身體的好處，但實際做了以後就會發現，它讓我們的身體與情緒都更強壯、更靈活。
第一次聽到，就讓我很感動的歌曲，一切盡在不言中（心有靈犀）
根據線上發表於11月21日外科學誌(Archives of Surgery)的研究，身體質量指數(BMI)較低的病患在一般手術與血管手術後30天內的死亡率比體重較重者高，校正其他與體重無關的病患本身或手術相關死亡率風險因素之後，此關聯依舊成立。
Researchers Say Acne Patients Should Consider Risks vs. Benefits of Treatment With Antibiotics
研究者建議痤瘡患者應該要考慮使用抗生素治療的風險收益
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