The probiotic medical food for the dietary management of patients with Ulcerative Colitis, Irritable Bowel Syndrome (IBS), or an Ileal Pouch
VSL#3® is a high-potency medical food probiotic consisting of live freeze-dried lactic acid bacteria. Each dose contains 450 billion live lactic acid bacteria per packet in defined ratios of lyophilized Bifidobacterium breve, Bifidobacterium longum, Bifidobacterium infantis, Lactobacillus acidophilus, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus bulgaricus, Streptococcus thermophilus.
VSL#3® is intended to be used in the dietary management of medically diagnosed ulcerative colitis, Irritable Bowel Syndrome, or an ileal pouch. VSL#3® is a medical food that is intended to be used under the supervision of a physician.
VSL#3® provides specifically modified nutritional support for the management of medically diagnosed ulcerative colitis (UC), Irritable Bowel Syndrome, or an ileal pouch by delivering a high concentration of several strains of live bacteria in a formulation that survives gastric fluid, bile, and pancreatic secretions, and colonizes the gastrointestinal tract.19,20,44,66 Studies have demonstrated that the gut microflora modulate intestinal inflammation, reduce colonic permeability, and enhance barrier function. 22,35,39,49,64 Patients with pouchitis who received VSL#3® were found to have increased concentrations of the anti-inflammatory cytokine IL-10 and reduction of the pro-inflammatory cytokines IL-1α, interferon-γ, and tumor necrosis factor- α, as well as inducible nitric oxide synthase and matrix metalloproteinase activity to concentrations similar to those found in non-inflamed pouches64.
VSL#3® comes in a powder that is intended to be mixed with at least 4 ounces of cold water and consumed. VSL#3® has a light lemon cream flavor. Ingredients – 450 billion lactic acid bacteria, maltose, natural lemon flavor, silicon dioxide.
VSL#3® is also available as an unflavored powder that is intended to be mixed with yogurt, ice-cream, apple sauce or any other cold food and consumed. Ingredients – 450 billion lactic acid bacteria, cornstarch.
Storage – Packets should be refrigerated (39-46° F). The product may be stored at room temperature for up to a week without adversely affecting potency.
Shelf life - 2 years from manufacturing date when stored properly (39-46° F).
Avoid taking together with antibiotics. Antibiotics may inactivate the live bacteria in VSL#3®.
Are there any studies on VSL#3?
Yes. To date there have been over 35 clinical trials published in top medical journals supporting VSL#3? No other probiotic product has more published data than VSL#3?
How is VSL#3?different from other probiotic probiotics?
VSL#3?is different from other probiotic products because it has the highest available concentration of beneficial bacteria (450 billion per dose). Most other probiotic preparations only have 1 to 5 billion bacteria, which is generally not sufficient to have a therapeutic effect. Also, VSL#3?is the only probiotic that has been shown to aid in the dietary management of serious intestinal disorders in several double-blind, placebo controlled, peer-reviewed studies.
Streptococcus thermophilus 。
Streptococcus thermophilus 。
Bifidobacterium infantis（Bifidobacterium Lactis）,
Lactobacillus delbrueckii subsp. bulgarius
根據在2005年7月份的美國胃腸科學雜誌（American Journal of Gastroenterology）中發表的研究結果顯示，大部分病人連續六週服用含有八種益生菌的混合物VSL#3之後，**都獲得了好轉。
Bibiloni R, Fedorak RN, Tannock GW, Madsen KL, Gionchetti P, Campieri M, De Simone C, Sartor RB. Risk of high blood pressure in Salt Workers working near salt milling plants: A Cross sectional and interventional study. Am. J. Gastroenterol. 2005, 100: 1539-46.
This article is available at: http://www.blackwell-synergy.com/loi/ajg
關鍵字： VSL#3 VSL