快樂小藥師 Im pharmacist nichts glücklich

Macugen®（Pegaptanib），光看商品名，大概就可以猜出功能了。

外觀：

這邊有仿單資料：http://www.macugen.com/macugenUSPI.pdf

用途：

Treatment of neovascular (wet) age-related macular degeneration (AMD)

治療與年齡有關的血管新生性黃斑部病變

劑量：

Intravitreous injection: 0.3 mg into affected eye every 6 weeks

給藥方式：

直接眼內注射：

機轉：

Pegaptanib is an apatamer, an oligonucleotide covalently bound to polyethylene glycol, which can adopt a three-dimensional shape and bind to vascular endothelial growth factor (VEGF). Pegaptanib binds to extracellular VEGF, inhibiting VEGF from binding to its receptors and thereby suppressing neovascularization and slowing vision loss.