Drugs with a Risk of Torsades de Pointes 會引起Torsades de Pointes的藥物
Drugs with a Conditional Risk of Torsades de Pointes 有條件風險引起Torsades de Pointes的藥物
資料來源:http://www.azcert.org/medical-pros/drug-lists/drug-lists.cfm
|
Class/Clinical Use |
Comments |
|
Alfuzosin |
Uroxatral® |
Alpha1-blocker / Benign prostatic hyperplasia |
|
Artenimol+piperaquine |
Eurartesim® |
Anti-malarial / |
Not available in U.S. |
Atazanavir |
Reyataz® |
Protease inhibitor / HIV |
|
Bedaquiline |
Sirturo® |
Anti-infective / Drug-resistant Tuberculosis |
Black Box for QT |
Clozapine |
Clozaril® |
Anti-psychotic / schizophrenia |
|
Dolasetron |
Anzemet® |
Anti-nausea / nausea, vomiting |
|
Dronedarone |
Multaq® |
Anti-arrhythmic / Atrial Fibrillation |
|
Eribulin |
Halaven® |
Anti-cancer / metastatic breast neoplasias |
|
Famotidine |
Pepcid® |
H2-receptor antagonist / Peptic ulcer/ GERD |
|
Felbamate |
Felbatol® |
Anti-convulsant / seizure |
|
Fingolimod |
Gilenya® |
Immunosuppressant / Multiple Sclerosis |
|
Foscarnet |
Foscavir® |
Anti-viral / HIV infection |
|
Fosphenytoin |
Cerebyx® |
Anti-convulsant / seizure |
|
Gatifloxacin |
Tequin® |
Antibiotic / bacterial infection |
Oral/I.V. forms no longer available in U.S. and Canada, only ophthalmic |
Gemifloxacin |
Factive® |
Antibiotic / bacterial infection |
|
Granisetron |
Kytril® |
Anti-nausea / nausea and vomiting |
|
Iloperidone |
Fanapt® |
Antipsychotic, atypical / Schizophrenia |
|
Indapamide |
Lozol® |
Diuretic / stimulate urine & salt loss |
|
Isradipine |
Dynacirc® |
Anti-hypertensive / high blood pressure |
|
Lapatinib |
Tykerb® |
Anti-cancer / breast cancer, metastatic |
|
Lapatinib |
Tyverb® |
Anti-cancer / breast cancer, metastatic |
|
Levofloxacin |
Levaquin® |
Antibiotic / bacterial infection |
|
Lithium |
Eskalith® |
Anti-mania / bipolar disorder |
|
Lithium |
Lithobid® |
Anti-mania / bipolar disorder |
|
Mirtazapine |
Remeron |
Anti-depressant / |
|
Moexipril/HCTZ |
Uniretic® |
Anti-hypertensive / high blood pressure |
|
Nicardipine |
Cardene® |
Anti-hypertensive / high blood pressure |
|
Nilotinib |
Tasigna® |
Anti-cancer / Leukemia |
|
Ofloxacin |
Floxin® |
Antibiotic / bacterial infection |
|
Olanzapine |
Zyprexa® |
Antipsychotic, atypical / Schizophrenia, bipolar |
Combo c fluoxetine: Symbyax |
Ondansetron |
Zofran® |
Anti-emetic / nausea and vomiting |
|
Oxytocin |
Pitocin® |
Oxytocic / Labor stimulation |
|
Paliperidone |
Invega® |
Antipsychotic, atypical / Schizophrenia |
|
Pasireotide |
Signifor® |
Somatostatin analog / Cushings Disease |
|
Perflutren lipid microspheres |
Definity® |
Imaging contrast agent / Echocardiography |
|
Promethazine |
Phenergan |
anti-emetic / nausea |
|
Quetiapine |
Seroquel® |
Anti-psychotic / schizophrenia |
|
Ranolazine |
Ranexa® |
Anti-anginal / chronic angina |
|
Rilpivirine |
Edurant® |
Anti-viral / HIV/AIDS |
Complera® and Eviplera® are combination products containing Rilpivirine |
Rilpivirine |
Complera® |
Anti-viral / HIV/AIDS |
Complera® and Eviplera® are combination products containing Rilpivirine |
Rilpivirine |
Eviplera® |
Anti-viral / HIV/AIDS |
Complera® and Eviplera® are combination products containing Rilpivirine |
Risperidone |
Risperdal® |
Anti-psychotic / schizophrenia |
|
Roxithromycin* |
Rulide® |
Antibiotic / bacterial infection |
*Not available in U.S. |
Saquinavir |
Invirase®(combo) |
Anti-viral / HIV/AIDS |
|
Sertindole |
Serdolect® |
Antipsychotic, atypical / Anxiety, Schizophrenia |
Not available in U.S. |
Sertindole |
Serlect® |
Antipsychotic, atypical / Anxiety, Schizophrenia |
Not available in U.S. |
Sunitinib |
Sutent® |
Anti-cancer / RCC, GIST |
|
Tacrolimus |
Prograf® |
Immunosuppressant / Immune suppression |
|
Tamoxifen |
Nolvadex brand discontinued 6/13 |
Anti-cancer / breast cancer |
|
Telavancin |
Vibativ® |
Antibiotic / Bacterial infection |
|
Telithromycin |
Ketek® |
Antibiotic / bacterial infection |
|
Tizanidine |
Zanaflex® |
Muscle relaxant / |
|
Tolterodine |
Detrol® |
Bladder Antispasmodic / |
Also available as Detrol LA® |
Vardenafil |
Levitra® |
phosphodiesterase inhibitor / vasodilator |
|
Venlafaxine |
Effexor® |
Anti-depressant / depression |
|
Voriconazole |
VFend® |
Anti-fungal / anti-fungal |
|
Ziprasidone |
Geodon® |
Anti-psychotic / schizophrenia |
|
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