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Drugs with a Risk of Torsades de Pointes 會引起Torsades de Pointes的藥物

Drugs with a Conditional Risk of Torsades de Pointes 有條件風險引起Torsades de Pointes的藥物

資料來源:http://www.azcert.org/medical-pros/drug-lists/drug-lists.cfm

 

Generic Name

Brand Name

 

Class/Clinical Use

Comments

Alfuzosin

Uroxatral®

Alpha1-blocker / Benign prostatic hyperplasia

 

Artenimol+piperaquine

Eurartesim®

Anti-malarial /

Not available in U.S.

Atazanavir

Reyataz®

Protease inhibitor / HIV

 

Bedaquiline

Sirturo®

Anti-infective / Drug-resistant Tuberculosis

Black Box for QT

Clozapine

Clozaril®

Anti-psychotic / schizophrenia

 

Dolasetron

Anzemet®

Anti-nausea / nausea, vomiting

 

Dronedarone

Multaq®

Anti-arrhythmic / Atrial Fibrillation

 

Eribulin

Halaven®

Anti-cancer / metastatic breast neoplasias

 

Famotidine

Pepcid®

H2-receptor antagonist / Peptic ulcer/ GERD

 

Felbamate

Felbatol®

Anti-convulsant / seizure

 

Fingolimod

Gilenya®

Immunosuppressant / Multiple Sclerosis

 

Foscarnet

Foscavir®

Anti-viral / HIV infection

 

Fosphenytoin

Cerebyx®

Anti-convulsant / seizure

 

Gatifloxacin

Tequin®

Antibiotic / bacterial infection

Oral/I.V. forms no longer available in U.S. and Canada, only ophthalmic

Gemifloxacin

Factive®

Antibiotic / bacterial infection

 

Granisetron

Kytril®

Anti-nausea / nausea and vomiting

 

Iloperidone

Fanapt®

Antipsychotic, atypical / Schizophrenia

 

Indapamide

Lozol®

Diuretic / stimulate urine & salt loss

 

Isradipine

Dynacirc®

Anti-hypertensive / high blood pressure

 

Lapatinib

Tykerb®

Anti-cancer / breast cancer, metastatic

 

Lapatinib

Tyverb®

Anti-cancer / breast cancer, metastatic

 

Levofloxacin

Levaquin®

Antibiotic / bacterial infection

 

Lithium

Eskalith®

Anti-mania / bipolar disorder

 

Lithium

Lithobid®

Anti-mania / bipolar disorder

 

Mirtazapine

Remeron

Anti-depressant /

 

Moexipril/HCTZ

Uniretic®

Anti-hypertensive / high blood pressure

 

Nicardipine

Cardene®

Anti-hypertensive / high blood pressure

 

Nilotinib

Tasigna®

Anti-cancer / Leukemia

 

Ofloxacin

Floxin®

Antibiotic / bacterial infection

 

Olanzapine

Zyprexa®

Antipsychotic, atypical / Schizophrenia, bipolar

Combo c fluoxetine: Symbyax

Ondansetron

Zofran®

Anti-emetic / nausea and vomiting

 

Oxytocin

Pitocin®

Oxytocic / Labor stimulation

 

Paliperidone

Invega®

Antipsychotic, atypical / Schizophrenia

 

Pasireotide

Signifor®

Somatostatin analog / Cushings Disease

 

Perflutren lipid microspheres

Definity®

Imaging contrast agent / Echocardiography

 

Promethazine

Phenergan

anti-emetic / nausea

 

Quetiapine

Seroquel®

Anti-psychotic / schizophrenia

 

Ranolazine

Ranexa®

Anti-anginal / chronic angina

 

Rilpivirine

Edurant®

Anti-viral / HIV/AIDS

Complera® and Eviplera® are combination products containing Rilpivirine

Rilpivirine

Complera®

Anti-viral / HIV/AIDS

Complera® and Eviplera® are combination products containing Rilpivirine

Rilpivirine

Eviplera®

Anti-viral / HIV/AIDS

Complera® and Eviplera® are combination products containing Rilpivirine

Risperidone

Risperdal®

Anti-psychotic / schizophrenia

 

Roxithromycin*

Rulide®

Antibiotic / bacterial infection

*Not available in U.S.

Saquinavir

Invirase®(combo)

Anti-viral / HIV/AIDS

 

Sertindole

Serdolect®

Antipsychotic, atypical / Anxiety, Schizophrenia

Not available in U.S.

Sertindole

Serlect®

Antipsychotic, atypical / Anxiety, Schizophrenia

Not available in U.S.

Sunitinib

Sutent®

Anti-cancer / RCC, GIST

 

Tacrolimus

Prograf®

Immunosuppressant / Immune suppression

 

Tamoxifen

Nolvadex brand discontinued 6/13

Anti-cancer / breast cancer

 

Telavancin

Vibativ®

Antibiotic / Bacterial infection

 

Telithromycin

Ketek®

Antibiotic / bacterial infection

 

Tizanidine

Zanaflex®

Muscle relaxant /

 

Tolterodine

Detrol®

Bladder Antispasmodic /

Also available as Detrol LA®

Vardenafil

Levitra®

phosphodiesterase inhibitor / vasodilator

 

Venlafaxine

Effexor®

Anti-depressant / depression

 

Voriconazole

VFend®

Anti-fungal / anti-fungal

 

Ziprasidone

Geodon®

Anti-psychotic / schizophrenia

 

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