Drugs with a Possible Risk of Torsades de Pointes 可能引起Torsades de Pointes的藥物
Drugs with a Conditional Risk of Torsades de Pointes 有條件引起Torsades de Pointes的藥物
資料來源:http://www.azcert.org/medical-pros/drug-lists/drug-lists.cfm
Class/Clinical Use |
Comments |
||
Amiodarone |
Cordarone® |
Anti-arrhythmic / abnormal heart rhythm |
Females>Males,TdP risk regarded as low |
Amiodarone |
Pacerone® |
Anti-arrhythmic / abnormal heart rhythm |
Females>Males,TdP risk regarded as low |
Arsenic trioxide |
Trisenox® |
Anti-cancer / Leukemia |
|
Astemizole |
Hismanal® |
Antihistamine / Allergic rhinitis |
No Longer available in U.S. |
Azithromycin |
Zithromax® |
Antibiotic / bacterial infection |
|
Bepridil |
Vascor® |
Anti-anginal / heart pain |
Females>Males |
Chloroquine |
Aralen® |
Anti-malarial / malaria infection |
|
Chlorpromazine |
Thorazine® |
Anti-psychotic/ Anti-emetic / schizophrenia/ nausea |
|
Cisapride |
Propulsid® |
GI stimulant / heartburn |
No longer available in U.S. |
Citalopram |
Celexa® |
Anti-depressant / depression |
|
Clarithromycin |
Biaxin® |
Antibiotic / bacterial infection |
|
Disopyramide |
Norpace® |
Anti-arrhythmic / abnormal heart rhythm |
Females>Males |
Dofetilide |
Tikosyn® |
Anti-arrhythmic / abnormal heart rhythm |
Females > Males |
Domperidone |
Motilium® |
Anti-nausea / nausea |
Not available in U.S. |
Droperidol |
Inapsine® |
Sedative;Anti-nausea / anesthesia adjunct, nausea |
|
Erythromycin |
E.E.S.® |
Antibiotic;GI stimulant / bacterial infection; increase GI motility |
Females>Males |
Erythromycin |
Erythrocin® |
Antibiotic;GI stimulant / bacterial infection; increase GI motility |
Females>Males |
Escitalopram |
Cipralex® |
Anti-depressant / Major depression/ Anxiety disorders |
Changed from Possible Risk to Risk- 12/2/12 |
Escitalopram |
Lexapro® |
Anti-depressant / Major depression/ Anxiety disorders |
Changed from Possible Risk to Risk- 12/2/12 |
Flecainide |
Tambocor® |
Anti-arrhythmic / abnormal heart rhythm |
|
Halofantrine |
Halfan® |
Anti-malarial / malaria infection |
Females>Males |
Haloperidol |
Haldol® |
Anti-psychotic / schizophrenia, agitation |
TdP risk with I.V. or excess dosage |
Ibutilide |
Corvert® |
Anti-arrhythmic / abnormal heart rhythm |
Females>Males |
Levomethadyl |
Orlaam® |
Opiate agonist / pain control, narcotic dependence |
Not available in U.S. |
Mesoridazine |
Serentil® |
Anti-psychotic / schizophrenia |
Removed from US market in 2004 |
Methadone |
Dolophine® |
Opiate agonist / pain control, narcotic dependence |
Females>Males |
Methadone |
Methadose® |
Opiate agonist / pain control, narcotic dependence |
Females>Males |
Moxifloxacin |
Avelox® |
Antibiotic / bacterial infection |
|
Pentamidine |
NebuPent® |
Anti-infective / pneumocystis pneumonia |
Females>Males |
Pentamidine |
Pentam® |
Anti-infective / pneumocystis pneumonia |
Females>Males |
Pimozide |
Orap® |
Anti-psychotic / Tourette's tics |
Females>Males |
Probucol |
Lorelco® |
Antilipemic / Hypercholesterolemia |
No longer available in U.S. |
Procainamide |
Pronestyl® |
Anti-arrhythmic / abnormal heart rhythm |
|
Procainamide |
Procan® |
Anti-arrhythmic / abnormal heart rhythm |
|
Quinidine |
Quinaglute® |
Anti-arrhythmic / abnormal heart rhythm |
Females>Males |
Quinidine |
Cardioquin® |
Anti-arrhythmic / abnormal heart rhythm |
Females>Males |
Sevoflurane |
Ulane® |
Anesthetic, general / anesthesia |
Label warning for patients with congenital long QT or patients taking QT prolonging drugs
|
Sevoflurane |
Sojourn® |
Anesthetic, general / anesthesia |
Label warning for patients with congenital long QT or patients taking QT prolonging drugs
|
Sotalol |
Betapace® |
Anti-arrhythmic / abnormal heart rhythm |
Females>Males |
Sparfloxacin |
Zagam® |
Antibiotic / bacterial infection |
No longer available in U.S. |
Terfenadine |
Seldane® |
Antihistamine / Allergic rhinitis |
No longer available in U.S. |
Thioridazine |
Mellaril® |
Anti-psychotic / schizophrenia |
|
Vandetanib |
Caprelsa® |
Anti-cancer / Thyroid cancer |
|
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