Drugs with a Risk of Torsades de Pointes.jpg  

Drugs with a Possible Risk of Torsades de Pointes 可能引起Torsades de Pointes的藥物

 

Drugs with a Conditional Risk of Torsades de Pointes 有條件引起Torsades de Pointes的藥物

資料來源:http://www.azcert.org/medical-pros/drug-lists/drug-lists.cfm

Generic Name

Brand Name

Class/Clinical Use

Comments

Amiodarone

Cordarone®

Anti-arrhythmic / abnormal heart rhythm

Females>Males,TdP risk regarded as low

Amiodarone

Pacerone®

Anti-arrhythmic / abnormal heart rhythm

Females>Males,TdP risk regarded as low

Arsenic trioxide

Trisenox®

Anti-cancer / Leukemia

 

Astemizole

Hismanal®

Antihistamine / Allergic rhinitis

No Longer available in U.S.

Azithromycin

Zithromax®

Antibiotic / bacterial infection

 

Bepridil

Vascor®

Anti-anginal / heart pain

Females>Males

Chloroquine

Aralen®

Anti-malarial / malaria infection

 

Chlorpromazine

Thorazine®

Anti-psychotic/ Anti-emetic / schizophrenia/ nausea

 

Cisapride

Propulsid®

GI stimulant / heartburn

No longer available in U.S.
 

Citalopram

Celexa®

Anti-depressant / depression

 

Clarithromycin

Biaxin®

Antibiotic / bacterial infection

 

Disopyramide

Norpace®

Anti-arrhythmic / abnormal heart rhythm

Females>Males

Dofetilide

Tikosyn®

Anti-arrhythmic / abnormal heart rhythm

Females > Males

Domperidone

Motilium®

Anti-nausea / nausea

Not available in U.S.

Droperidol

Inapsine®

Sedative;Anti-nausea / anesthesia adjunct, nausea

 

Erythromycin

E.E.S.®

Antibiotic;GI stimulant / bacterial infection; increase GI motility

Females>Males

Erythromycin

Erythrocin®

Antibiotic;GI stimulant / bacterial infection; increase GI motility

Females>Males

Escitalopram

Cipralex®

Anti-depressant / Major depression/ Anxiety disorders

 Changed from Possible Risk to Risk- 12/2/12

Escitalopram

Lexapro®

Anti-depressant / Major depression/ Anxiety disorders

 Changed from Possible Risk to Risk- 12/2/12

Flecainide

Tambocor®

Anti-arrhythmic / abnormal heart rhythm

 

Halofantrine

Halfan®

Anti-malarial / malaria infection

Females>Males

Haloperidol

Haldol®

Anti-psychotic / schizophrenia, agitation

TdP risk with I.V. or excess dosage

Ibutilide

Corvert®

Anti-arrhythmic / abnormal heart rhythm

Females>Males

Levomethadyl

Orlaam®

Opiate agonist / pain control, narcotic dependence

Not available in U.S.

Mesoridazine

Serentil®

Anti-psychotic / schizophrenia

Removed from US market in 2004

Methadone

Dolophine®

Opiate agonist / pain control, narcotic dependence

Females>Males

Methadone

Methadose®

Opiate agonist / pain control, narcotic dependence

Females>Males

Moxifloxacin

Avelox®

Antibiotic / bacterial infection

 

Pentamidine

NebuPent®

Anti-infective / pneumocystis pneumonia

Females>Males

Pentamidine

Pentam®

Anti-infective / pneumocystis pneumonia

Females>Males

Pimozide

Orap®

Anti-psychotic / Tourette's tics

Females>Males

Probucol

Lorelco®

Antilipemic / Hypercholesterolemia

No longer available in U.S.

Procainamide

Pronestyl®

Anti-arrhythmic / abnormal heart rhythm

 

Procainamide

Procan®

Anti-arrhythmic / abnormal heart rhythm

 

Quinidine

Quinaglute®

Anti-arrhythmic / abnormal heart rhythm

Females>Males

Quinidine

Cardioquin®

Anti-arrhythmic / abnormal heart rhythm

Females>Males

Sevoflurane

Ulane®

Anesthetic, general / anesthesia

Label warning for patients with congenital long QT or patients taking QT prolonging drugs

 

Sevoflurane

Sojourn®

Anesthetic, general / anesthesia

Label warning for patients with congenital long QT or patients taking QT prolonging drugs

 

Sotalol

Betapace®

Anti-arrhythmic / abnormal heart rhythm

Females>Males

Sparfloxacin

Zagam®

Antibiotic / bacterial infection

No longer available in U.S.

Terfenadine

Seldane®

Antihistamine / Allergic rhinitis

No longer available in U.S.

Thioridazine

Mellaril®

Anti-psychotic / schizophrenia

 

Vandetanib

Caprelsa®

Anti-cancer / Thyroid cancer

 

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