Drugs with a Risk of Torsades de Pointes 會引起Torsades de Pointes風險的藥物
Drugs with a Possible Risk of Torsades de Pointes 可能引起Torsades de Pointes的藥物
資料來源：http://www.azcert.org/medical-pros/drug-lists/drug-lists.cfm
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Class/Clinical Use |
Comments |
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Amantadine |
Symmetrel® |
Dopaminergic/Anti-viral / Anti-infective/ Parkinson's Disease |
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Amisulpride |
Solian® and others |
Antipsychotic, atypical / |
Risk of TdP with overdose - not available in US |
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Amitriptyline |
Elavil® (Discontinued 6/13) |
Tricyclic Antidepressant / depression |
Risk of TdP with overdosage |
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Chloral hydrate |
Noctec® |
Sedative / sedation/ insomnia |
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Ciprofloxacin |
Cipro® |
Antibiotic / bacterial infection |
Drug interaction risk - metabolic inhibitor |
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Clomipramine |
Anafranil® |
Tricyclic Antidepressant / depression |
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Desipramine |
Pertofrane® |
Tricyclic Antidepressant / depression |
Risk of TdP with overdosage |
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Diphenhydramine |
Benadryl® |
Antihistamine / Allergic rhinitis, insomnia |
Risk of QT increase/TdP in overdosages |
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Diphenhydramine |
Nytol® |
Antihistamine / Allergic rhinitis, insomnia |
Risk of QT increase/TdP in overdosages |
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Doxepin |
Sinequan® |
Tricyclic Antidepressant / depression |
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Fluconazole |
Diflucan® |
Anti-fungal / fungal infection |
Drug interaction risk- metabolic inhibitor. Can also increase QT at high doses - 800 mg/day |
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Fluoxetine |
Sarafem® |
Anti-depressant / depression |
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Fluoxetine |
Prozac® |
Anti-depressant / depression |
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Galantamine |
Reminyl® |
Cholinesterase inhibitor / Dementia, Alzheimer's |
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Imipramine |
Norfranil® |
Tricyclic Antidepressant / depression |
TdP risk with excess dosage |
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Itraconazole |
Sporanox® |
Anti-fungal / fungal infection |
Drug interaction risk - metabolic inhibitor |
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Ketoconazole |
Nizoral® |
Anti-fungal / fungal infection |
Prolongs QT & Drug interaction risk - metabolic inhibitor. |
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Nortriptyline |
Pamelor® |
Tricyclic Antidepressant / depression |
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Paroxetine |
Paxil® |
Anti-depressant / depression |
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Protriptyline |
Vivactil® |
Tricyclic Antidepressant / depression |
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Quinine sulfate |
Qualaquin® |
Anti-malarial / Malaria or leg cramps |
TdP with overdose or drug-drug or drug food interaction |
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Ritonavir |
Norvir® |
Protease inhibitor / HIV |
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Sertraline |
Zoloft® |
Anti-depressant / depression |
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Solifenacin |
VESIcare® |
muscarinic receptor anatagonist / treatment of overactive bladder |
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Trazodone |
Desyrel® (brand discontinued 6/13) |
Anti-depressant / Depression, insomnia |
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Trimethoprim-Sulfa |
Septra® or Bactrim® |
Antibiotic / bacterial infection |
Also available in DS (double strength) |
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Trimipramine |
Surmontil® |
Tricyclic Antidepressant / depression |
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