Class I 最強；VII最弱
更新到2019
Comparison of representative topical corticosteroid preparations (classified according to the US system)
|
Potency group* |
Corticosteroid |
Vehicle type/form |
Trade names |
Available strength(s), percent |
|
Super-high potency |
Betamethasone dipropionate, augmented |
Ointment, optimized |
Diprolene |
0.05 |
|
Lotion |
Diprolene |
0.05 |
||
|
Gel |
Diprolene |
0.05 |
||
|
Clobetasol propionate |
Ointment |
Temovate |
0.05 |
|
|
Cream |
Temovate |
0.05 |
||
|
Cream, emollient base |
Temovate E |
0.05 |
||
|
Gel |
Temovate |
0.05 |
||
|
Lotion |
Clobex |
0.05 |
||
|
Foam aerosol |
Olux-E |
0.05 |
||
|
Foam aerosol (scalp) |
Olux |
0.05 |
||
|
Shampoo |
Clobex |
0.05 |
||
|
Solution (scalp) |
Temovate, Cormax |
0.05 |
||
|
Spray aerosol |
Clobex |
0.05 |
||
|
Diflucortolone valerate (not available in United States) |
Ointment, oily cream |
Nerisone Forte (United Kingdom, others) |
0.3 |
|
|
Fluocinonide |
Cream |
Vanos |
0.1 |
|
|
Flurandrenolide |
Tape (roll) |
Cordran |
4 mcg/cm2 |
|
|
Halobetasol propionate |
Ointment |
Ultravate |
0.05 |
|
|
Cream |
Ultravate |
0.05 |
||
|
Lotion |
Ultravate |
0.05 |
||
|
High potency |
Amcinonide |
Ointment |
Cyclocort¶, Amcort¶ |
0.1 |
|
Betamethasone dipropionate |
Ointment |
Diprosone |
0.05 |
|
|
Cream, augmented formulation (AF) |
Diprolene AF |
0.05 |
||
|
Clobetasol propionate |
Cream |
Impoyz |
0.025 |
|
|
Desoximetasone |
Ointment |
Topicort |
0.25 |
|
|
Cream |
Topicort |
0.25 |
||
|
Spray |
Topicort |
0.25 |
||
|
Gel |
Topicort |
0.05 |
||
|
Diflorasone diacetate |
Ointment |
ApexiCon¶, Florone¶ |
0.05 |
|
|
Cream, emollient |
ApexiCon E |
0.05 |
||
|
Fluocinonide |
Ointment |
Lidex¶ |
0.05 |
|
|
Gel |
Lidex¶ |
0.05 |
||
|
Cream anhydrous |
Lidex¶ |
0.05 |
||
|
Solution |
Lidex¶ |
0.05 |
||
|
Halcinonide |
Ointment |
Halog |
0.1 |
|
|
Cream |
Halog |
0.1 |
||
|
Halobetasol propionate |
Lotion |
Bryhali |
0.01 |
|
|
High potency |
Amcinonide |
Cream |
Cyclocort¶, Amcort¶ |
0.1 |
|
Lotion |
Amcort¶ |
0.1 |
||
|
Betamethasone dipropionate |
Cream, hydrophilic emollient |
Diprosone |
0.05 |
|
|
Betamethasone valerate |
Ointment |
Valisone¶ |
0.1 |
|
|
Foam |
Luxiq |
0.12 |
||
|
Desoximetasone |
Cream |
Topicort LP |
0.05 |
|
|
Diflorasone diacetate |
Cream |
Florone¶ |
0.05 |
|
|
Diflucortolone valerate (not available in United States) |
Cream, oily cream, ointment |
Nerisone (Canada, United Kingdom, others) |
0.1 |
|
|
Fluocinonide |
Cream aqueous emollient |
Lidex-E¶ |
0.05 |
|
|
Fluticasone propionate |
Ointment |
Cutivate |
0.005 |
|
|
Mometasone furoate |
Ointment |
Elocon |
0.1 |
|
|
Triamcinolone acetonide |
Ointment |
Kenalog¶ |
0.5 |
|
|
Cream |
Triderm, Aristocort HP¶ |
0.5 |
||
|
Medium potency |
Betamethasone dipropionate |
Spray |
Sernivo |
0.05 |
|
Clocortolone pivalate |
Cream |
Cloderm |
0.1 |
|
|
Fluocinolone acetonide |
Ointment |
Synalar¶ |
0.025 |
|
|
Flurandrenolide |
Ointment |
Cordran |
0.05 |
|
|
Hydrocortisone valerate |
Ointment |
Westcort |
0.2 |
|
|
Mometasone furoate |
Cream |
Elocon |
0.1 |
|
|
Lotion |
Elocon |
0.1 |
||
|
Solution |
Elocon¶ |
0.1 |
||
|
Triamcinolone acetonide |
Cream |
Kenalog¶ |
0.1 |
|
|
Ointment |
Kenalog¶ |
0.1 |
||
|
Aerosol spray |
Kenalog |
0.2 mg per 2 second spray |
||
|
Lower-mid potency |
Betamethasone dipropionate |
Lotion |
Diprosone |
0.05 |
|
Betamethasone valerate |
Cream |
Beta-Val, Valisone¶ |
0.1 |
|
|
Desonide |
Ointment |
DesOwen, Tridesilon¶ |
0.05 |
|
|
Gel |
Desonate |
0.05 |
||
|
Fluocinolone acetonide |
Cream |
Synalar¶ |
0.025 |
|
|
Flurandrenolide |
Cream |
Cordran |
0.05 |
|
|
Lotion |
Cordran |
0.05 |
||
|
Fluticasone propionate |
Cream |
Cutivate |
0.05 |
|
|
Lotion |
Cutivate |
0.05 |
||
|
Hydrocortisone butyrate |
Ointment |
Locoid |
0.1 |
|
|
Cream |
Locoid, Locoid Lipocream |
0.1 |
||
|
Lotion, spray |
Cortizone 10 maximum |
0.1 |
||
|
Lotion |
Locoid |
0.1 |
||
|
Solution |
Locoid |
0.1 |
||
|
Hydrocortisone probutate |
Cream |
Pandel |
0.1 |
|
|
Hydrocortisone valerate |
Cream |
Westcort¶ |
0.2 |
|
|
Prednicarbate |
Cream, emollient |
Dermatop |
0.1 |
|
|
Ointment |
Dermatop |
0.1 |
||
|
Triamcinolone acetonide |
Lotion |
Kenalog¶ |
0.1 |
|
|
Ointment |
Kenalog¶ |
0.025 |
||
|
Low potency |
Alclometasone dipropionate |
Ointment |
Aclovate |
0.05 |
|
Cream |
Aclovate |
0.05 |
||
|
Betamethasone valerate |
Lotion |
Beta-Val, Valisone¶ |
0.1 |
|
|
Desonide |
Cream |
DesOwen, Tridesilon¶ |
0.05 |
|
|
Lotion |
DesOwen, LoKara |
0.05 |
||
|
Foam |
Verdeso |
0.05 |
||
|
Fluocinolone acetonide |
Cream |
Synalar¶ |
0.01 |
|
|
Solution |
Synalar¶ |
0.01 |
||
|
Shampoo |
Capex |
0.01 |
||
|
Oil (scalp)Δ |
Derma-Smoothe/FS Scalp |
0.01 |
||
|
Oil (body)Δ |
Derma-Smoothe/FS Body |
0.01 |
||
|
Triamcinolone acetonide |
Cream |
Kenalog¶, Aristocort¶ |
0.025 |
|
|
Lotion |
Kenalog¶ |
0.025 |
||
|
Least potent |
Hydrocortisone (base, ≥2%) |
Ointment |
Hytone |
2.5 |
|
Cream |
Hytone, Nutracort¶ |
2.5 |
||
|
Lotion |
Hytone, Ala Scalp, Scalacort |
2.5 or 2 |
||
|
Solution |
Texacort |
2.5 |
||
|
Hydrocortisone (base, <2%) |
Ointment |
Cortaid, Hytone, Nutracort |
1 |
|
|
Cream |
Cortaid, Hytone, Synacort |
1 |
||
|
Lotion |
Aquanil HC, Sarnol-HC, Cortizone 10 |
1 |
||
|
Spray |
Cortaid |
1 |
||
|
Solution |
Cortaid, Noble, Scalp relief |
1 |
||
|
Ointment |
Cortaid |
0.5 |
||
|
Cream |
Cortaid |
0.5 |
||
|
Hydrocortisone acetate with pramoxine 1% combination |
Ointment |
Pramosone |
1 or 2.5 |
|
|
Cream |
Pramosone, Analpram-HC |
1 or 2.5 |
||
|
Lotion |
Pramosone, Analpram-HC |
1 or 2.5 |
||
|
Aerosol foam |
Epifoam |
1 |
US: United States.
* Listed by potency according to the US classification system: group 1 is the most potent, group 7 is the least potent. Other countries use a different classification system with only four or five groups.
¶ Inactive United States trade name for specific product; brand may be available outside United States.
Δ 48% refined peanut oil.
Data from:
1. Lexicomp Online. Copyright © 1978-2019 Lexicomp, Inc. All Rights Reserved.
2. Tadicherla S, Ross K, Shenefelt D. Topical corticosteroids in dermatology. Journal of Drugs in Dermatology 2009; 12:1093.
3. U.S. Food & Drug Administration Approved Drug Products with Therapeutic Equivalence (Orange Book). Available at: https://www.accessdata.fda.gov/scripts/cder/ob/default.cfm (Accessed on June 18, 2017).
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