Prediction of Compensatory Responses on Simple Acid-Base Disturbances | |
Disorder | Prediction of Compensation |
Metabolic acidosis | PaCO2 = (1.5 ´ HCO3-) + 8 |
or | |
PaCO2 will ¯ 1.25 mmHg per mmol/L ¯ in [HCO3-] | |
or | |
PaCO2 = [HCO3-] + 15 | |
Metabolic alkalosis | PaCO2 will ↑ 0.75 mmHg per mmol/L ↑ in [HCO3-] |
or | |
PaCO2 will ↑ 6 mmHg per 10 mmol/L ↑ in [HCO3-] | |
or | |
PaCO2 = [HCO3-] + 15 | |
Respiratory alkalosis | |
Acute | [HCO3-] will ¯ 2 mmol/L per 10 mmHg ¯ in PaCO2 |
Chronic | [HCO3-] will ¯ 4 mmol/L per 10 mmHg ¯ in PaCO2 |
Respiratory acidosis | |
Acute | [HCO3-] will ↑ 1 mmol/L per 10 mmHg ↑ in PaCO2 |
Chronic | [HCO3-] will ↑ 4 mmol/L per 10 mmHg ↑ in PaCO2 |
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