快樂小藥師 Im pharmacist nichts glücklich

CI monoclonal antibodies ("-mab")

Receptor tyrosine kinase

ErbB: HER1/EGFR (Cetuximab Panitumumab)

HER2/neu (Trastuzumab)

Others for solid tumors

EpCAM (Catumaxomab  Edrecolomab)

VEGF-A (Bevacizumab)

Leukemia/lymphoma

lymphoid: CD20 (Ibritumomab  Ofatumumab  Rituximab  Tositumomab),

CD30 (Brentuximab),

CD52 (Alemtuzumab)

myeloid: CD33 (Gemtuzumab)

Tyrosine-kinase inhibitors ("-nib")

Receptor tyrosine kinase

ErbB: HER1/EGFR (Erlotinib  Gefitinib  Vandetanib)

HER1/EGFR and HER2/neu (Afatinib  Lapatinib  Neratinib)

RTK class III: C-kit and PDGFR (Axitinib Pazopanib Sunitinib Sorafenib Toceranib)

FLT3 (Lestaurtinib)

VEGFR (Axitinib Cediranib Pazopanib Regorafenib Semaxanib Sorafenib Sunitinib Toceranib Vandetanib)

Non-receptor

bcr-abl (Dasatinib  Imatinib  Nilotinib)

Src (Bosutinib)

Janus kinase (Lestaurtinib  Ruxolitinib)

EML4-ALK (Crizotinib)

Other

fusion protein against VEGF (Aflibercept)

proapoptotic peptide against ANXA2 and prohibitin (Adipotide)

exotoxin against IL-2 (Denileukin diftitox)

mTOR inhibitors (Everolimus Temsirolimus)