What is the most important information I should know about Reclast?
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www.reclast.com/index.jsp
Reclast contains the same active ingredient (zoledronic acid) found in Zometa® Injection. If you are already being treated
with Zometa Injection, you should not receive Reclast Injection.
It is important to drink fluids before getting Reclast, and to take 1500 mg of calcium and 800 IU of vitamin D daily,
especially during the first 2 weeks after getting Reclast.
Patients with severe kidney problems should not receive Reclast Injection.
What is Reclast?
Reclast is a medicine to treat adults with Paget’s disease of bone.
What is Paget’s disease of bone?
Normally bone breaks down and is replaced by new bone. In Paget’s disease, bone breaks down too much and the new bone
made is not normal. Bones affected by Paget’s like the skull,spine, and legs, become deformed and weaker than normal.
This can cause problems like bone pain and the bones can bend or break. Paget’s disease may be discovered by X-ray
examination or blood tests.
How does Reclast work?
Reclast attaches to bone and keeps it from breaking down too much. A single dose works fast and keeps working to make your bones stronger again.
What are the possible side effects of Reclast?
Patients may get one or more side effects. The most common side effects are mild to moderate and happen within 3 days after
you get Reclast. They usually go away within 4 days after they start and could include:
• fever and chills
• pain in your muscles, bones or joints
• nausea
• fatigue
• headache
Skin reactions such as redness, swelling and/or pain at the infusion site may occur. Bisphosphonates (the group of drugs
that Reclast belongs to) may cause swelling, redness and itching to the eyes or eye sensitivity to light.
If you have questions about these side effects, talk to your doctor.
Some patients may experience low blood calcium after getting Reclast. Symptoms of low blood calcium may include numbness or tingling sensations (especially in the area around the mouth) or muscle spasms. Contact your doctor immediately if you notice any of these symptoms after getting Reclast.
There have been reports, primarily in patients treated with bisphosphonates for other illnesses, of persistent pain and/or
non-healing sore of the mouth or jaw. If you experience these symptoms tell your doctor or dentist.
How to Administer Reclast
看PDF：
www.reclast.com/hcp/tools/toolsprivate/pdfs/tear_sheet.pdf
網站連結：
www.reclast.com/index.jsp
Reclast contains the same active ingredient (zoledronic acid) found in Zometa® Injection. If you are already being treated
with Zometa Injection, you should not receive Reclast Injection.
It is important to drink fluids before getting Reclast, and to take 1500 mg of calcium and 800 IU of vitamin D daily,
especially during the first 2 weeks after getting Reclast.
Patients with severe kidney problems should not receive Reclast Injection.
What is Reclast?
Reclast is a medicine to treat adults with Paget’s disease of bone.
What is Paget’s disease of bone?
Normally bone breaks down and is replaced by new bone. In Paget’s disease, bone breaks down too much and the new bone
made is not normal. Bones affected by Paget’s like the skull,spine, and legs, become deformed and weaker than normal.
This can cause problems like bone pain and the bones can bend or break. Paget’s disease may be discovered by X-ray
examination or blood tests.
How does Reclast work?
Reclast attaches to bone and keeps it from breaking down too much. A single dose works fast and keeps working to make your bones stronger again.
What are the possible side effects of Reclast?
Patients may get one or more side effects. The most common side effects are mild to moderate and happen within 3 days after
you get Reclast. They usually go away within 4 days after they start and could include:
• fever and chills
• pain in your muscles, bones or joints
• nausea
• fatigue
• headache
Skin reactions such as redness, swelling and/or pain at the infusion site may occur. Bisphosphonates (the group of drugs
that Reclast belongs to) may cause swelling, redness and itching to the eyes or eye sensitivity to light.
If you have questions about these side effects, talk to your doctor.
Some patients may experience low blood calcium after getting Reclast. Symptoms of low blood calcium may include numbness or tingling sensations (especially in the area around the mouth) or muscle spasms. Contact your doctor immediately if you notice any of these symptoms after getting Reclast.
There have been reports, primarily in patients treated with bisphosphonates for other illnesses, of persistent pain and/or
non-healing sore of the mouth or jaw. If you experience these symptoms tell your doctor or dentist.
How to Administer Reclast
1. Preinfusion instructions (before patient's infusion appointment)
 |  | Confirm creatinine clearance is greater than or equal to 35 mL/min |
| ||
| | Confirm serum calcium is within normal range |
| ||
| | Instruct patient to drink fluids, such as water, within a few hours prior to infusion to ensure adequate hydration |
2. Instructions for use
| | Assemble supplies |
| ||
| | Obtain IV access (use of saline lock recommended for infusion) |
| ||
| | Prepare Reclast, open vent cap and prime tubing |
| ||
| | Infuse over no less than 15 minutes over a constant infusion rate |
| ||
| | Remove IV catheter and dispose of properly |
看PDF：
www.reclast.com/hcp/tools/toolsprivate/pdfs/tear_sheet.pdf
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