[up to date 18.2] Comparison of representative topical corticosteroid preparations－快樂小藥師 Im pharmacist nichts glücklich

Comparison of representative topical corticosteroid preparations

Potency group*	Corticosteroid	Vehicle type/form	Trade names (US)	Available strength(s), percent (except as noted)	Generic available in US•
Super high potency (group one)	Betamethasone dipropionate, augmented	Ointment, optimized	Diprolene®	0.05	Yes
		Lotion	Diprolene®	0.05	Yes
		Gel	Diprolene®	0.05	Yes
	Clobetasol propionate	Ointment	Temovate®	0.05	Yes
		Cream	Temovate®, Cormax®	0.05	Yes
		Cream, emollient base	Temovate E®	0.05	No
		Gel	Temovate®	0.05	Yes
		Lotion	Clobex®	0.05	No
		Foam aerosol	Olux-E®	0.05	No
		Foam aerosol (scalp)	Olux®	0.05	Yes
		Shampoo	Clobex®	0.05	No
		Solution (scalp)	Temovate®, Cormax®	0.05	Yes
		Spray aerosol	Clobex®	0.05	No
	Halobetasol propionate	Ointment	Ultravate®	0.05	Yes
	Halobetasol propionate	Cream	Ultravate®	0.05	Yes
	Fluocinonide	Cream	Vanos®	0.1	No
	Flurandrenolide	Tape (roll)	Cordran®	4 mcg/cm²	No
	Diflorasone diacetate	Ointment (petrolatum)	Psorcon®, ApexiCon®	0.05	Yes
High potency (group two)	Amcinonide	Ointment	Cyclocort®, Amcort®Δ	0.1	Yes
	Betamethasone dipropionate	Ointment	Diprosone®	0.05	Yes
	Betamethasone dipropionate	Cream, augmented formulation (AF)	Diprolene® AF	0.05	Yes
	Halcinonide	Ointment	Halog®	0.1	No
		Cream	Halog®	0.1	No
		Solution	Halog®	0.1	No
	Fluocinonide	Ointment	Lidex®	0.05	Yes
		Gel	Lidex®	0.05	Yes
		Cream anhydrous	Lidex®, Fluonex®	0.05	Yes
		Solution	Lidex®	0.05	Yes
	Diflorasone diacetate	Ointment, emollient	ApexiCon®, Psorcon E®Δ, Florone®Δ	0.05	Yes
	Diflorasone diacetate	Cream, emollient	ApexiCon® E, Psorcon E®Δ	0.05	Yes
	Desoximetasone	Ointment	Topicort®	0.25	Yes
		Cream	Topicort®	0.25	Yes
		Gel	Topicort®	0.05	Yes
	Triamcinolone acetonide	Ointment	Kenalog®Δ	0.5	Yes
High potency (group three)	Amcinonide	Cream	Cyclocort®, Amcort®Δ	0.1	Yes
	Amcinonide	Lotion	Amcort®Δ	0.1	Yes
	Betamethasone dipropionate	Cream, hydrophilic emollient	Diprosone®	0.05	Yes
	Betamethasone dipropionate	Lotion	Diprosone®	0.05	Yes
	Betamethasone valerate	Ointment	Valisone®Δ, Betatrex®Δ	0.1	Yes
	Betamethasone valerate	Foam	Luxiq®	0.12	No
	Fluticasone propionate	Ointment	Cutivate®	0.005	Yes
	Fluocinonide	Cream aqueous emollient	Lidex-E®	0.05	No
	Mometasone furoate	Ointment	Elocon®	0.1	Yes
	Desoximetasone	Cream	Topicort LP®	0.05	Yes
	Diflorasone diacetate	Cream	Maxiflor®Δ, Florone®Δ, Psorcon®Δ	0.05	Yes
	Triamcinolone acetonide	Ointment	Kenalog ®Δ	0.5	Yes
		Cream	Aristocort HP®Δ	0.5	Yes
		Ointment	Aristocort A®Δ	0.1	Yes
Medium potency (group four)
	Triamcinolone acetonide	Cream	Kenalog®Δ, Kenonel®	0.1	Yes
		Ointment	Kenalog®Δ	0.1	Yes
		Aerosol spray	Kenalog®	0.2 mg per 2 second spray	No
	Flurandrenolide	Ointment	Cordran®	0.05	No
	Fluocinolone acetonide	Ointment	Synalar®	0.025	Yes
	Mometasone furoate	Cream	Elocon®, Momexin®	0.1	Yes
		Lotion	Elocon®	0.1	Yes
		Solution	Elocon®Δ	0.1	Yes
	Hydrocortisone valerate	Ointment	Westcort®	0.2	Yes
	Clocortolone pivalate	Cream	Cloderm®	0.1	No

LIST CONTINUED IN TABLE "TOPICAL GLUCOCORTICOIDS II".

* Listed by potency: group one is the most potent, group seven is the least potent.
• Vehicle and base ingredient(s) for generic products, in some cases, may not be identical to trade version.
Δ Inactive US trade name for specific product; brand may be available outside US.

Data from: Lacy, CF et al (Eds) Lexi-Comp's Drug Information Handbook, 18th ed. Lexi-Comp Inc, Hudson OH. Copyright © 2010 and Tadicherla, S, Ross, K, Shenefelt, D, Topical corticosteroids in dermatology; Journal of Drugs in Dermatology 2009; 12:1093.

Comparison of representative topical corticosteroid preparations, continued

Potency group*	Corticosteroid	Vehicle type/form	Trade names (US)	Available strength(s), percent (except as noted)	Generic available in US•
Lower-mid potency (group five)	Triamcinolone acetonide	Lotion	Kenalog®Δ	0.1	Yes
	Triamcinolone acetonide	Ointment	Kenalog®Δ	0.025	Yes
	Betamethasone dipropionate	Lotion	Diprosone®	0.05	Yes
	Flurandrenolide	Cream	Cordran®	0.05	No
	Flurandrenolide	Lotion	Cordran®	0.05	No
	Fluticasone propionate	Cream	Cutivate®	0.05	Yes
	Fluticasone propionate	Lotion	Cutivate®	0.05	No
	Prednicarbate	Cream, emollient	Dermatop®	0.1	Yes
	Prednicarbate	Ointment	Dermatop®	0.1	Yes
	Desonide	Ointment	DesOwen®, Tridesilon®Δ	0.05	Yes
	Desonide	Gel	Desonate®	0.05	No
	Betamethasone valerate	Cream	Beta-Val®, Betatrex®Δ, Valisone®Δ	0.1	Yes
	Hydrocortisone valerate	Cream	Westcort®	0.2	Yes
	Hydrocortisone butyrate	Ointment	Locoid®	0.1	Yes
		Cream	Locoid®, Locoid Lipocream®	0.1	Yes
		Lotion, spray	Cortizone10® maximum	0.1	No
		Solution	Locoid®	0.1	Yes
	Hydrocortisone probutate	Cream	Pandel®	0.1	No
	Fluocinolone acetonide	Cream	Synalar®	0.025	Yes
Low potency (group six)	Alclometasone dipropionate	Ointment	Aclovate®	0.05	Yes
	Alclometasone dipropionate	Cream	Aclovate®	0.05	Yes
	Triamcinolone acetonide	Cream	Kenalog®Δ, Aristocort®Δ	0.025	Yes
	Triamcinolone acetonide	Lotion	Kenalog®Δ	0.025	Yes
	Desonide	Cream	DesOwen® , Tridesilon®Δ	0.05	Yes
		Lotion	DesOwen®, LoKara®	0.05	Yes
		Foam	Verdeso®	0.05	No
	Betamethasone valerate	Lotion	Beta-Val®, Valisone®Δ	0.1	Yes
	Fluocinolone acetonide	Cream	Synalar®	0.01	Yes
		Solution	Synalar®	0.01	Yes
		Shampoo	Capex®	0.01	No
		Oil (scalp)◊	Derma-Smoothe/FS®	0.01	No
		Oil (body)◊	Derma-Smoothe/FS®	0.01	No
Least potent (group seven)	Hydrocortisone (base)	Ointment	Hytone®	2.5	Yes
		Cream	Hytone®, Nutracort®	2.5	Yes
		Lotion	Hytone®	2.5	Yes
		Solution	Texacort®	2.5	Yes
	Hydrocortisone acetate with pramoxine 1 percent combination	Ointment	Pramosone®	1	Yes
		Cream	Pramosone®, Analpram HC	1	Yes
		Lotion	Cortane B Lotion®	1	Yes
		Aerosol foam	Epifoam®	1	Yes
	Hydrocortisone (base)	Ointment	Cortaid®, Hytone®, Nutracort®	1	Yes
		Cream	Cortaid®, Hytone®, Synacort	1	Yes
		Lotion	Cetacort®, Hytone®, Nutracort®	1	Yes
		Spray	Cortaid®	1	Yes
		Ointment	Lanacort-5®, Cortaid®	0.5	Yes
		Cream	Lanacort-5®, Cortaid®	0.5	Yes