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Comparison of representative topical corticosteroid preparations

Potency group*

Corticosteroid

Vehicle type/form

Trade names (US)

Available strength(s), percent (except as noted)

Generic available in US•

Super high potency (group one)

Betamethasone dipropionate, augmented

Ointment, optimized

Diprolene®

0.05

Yes

Lotion

Diprolene®

0.05

Yes

Gel

Diprolene®

0.05

Yes

Clobetasol propionate

Ointment

Temovate®

0.05

Yes

Cream

Temovate®, Cormax®

0.05

Yes

Cream, emollient base

Temovate E®

0.05

No

Gel

Temovate®

0.05

Yes

Lotion

Clobex®

0.05

No

Foam aerosol

Olux-E®

0.05

No

Foam aerosol (scalp)

Olux®

0.05

Yes

Shampoo

Clobex®

0.05

No

Solution (scalp)

Temovate®, Cormax®

0.05

Yes

Spray aerosol

Clobex®

0.05

No

Halobetasol propionate

Ointment

Ultravate®

0.05

Yes

Cream

Ultravate®

0.05

Yes

Fluocinonide

Cream

Vanos®

0.1

No

Flurandrenolide

Tape (roll)

Cordran®

4 mcg/cm2

No

Diflorasone diacetate

Ointment (petrolatum)

Psorcon®, ApexiCon®

0.05

Yes

High potency (group two)

Amcinonide

Ointment

Cyclocort®, Amcort®Δ

0.1

Yes

Betamethasone dipropionate

Ointment

Diprosone®

0.05

Yes

Cream, augmented formulation (AF)

Diprolene® AF

0.05

Yes

Halcinonide

Ointment

Halog®

0.1

No

Cream

Halog®

0.1

No

Solution

Halog®

0.1

No

Fluocinonide

Ointment

Lidex®

0.05

Yes

Gel

Lidex®

0.05

Yes

Cream anhydrous

Lidex®, Fluonex®

0.05

Yes

Solution

Lidex®

0.05

Yes

Diflorasone diacetate

Ointment, emollient

ApexiCon®, Psorcon E®Δ, Florone®Δ

0.05

Yes

Cream, emollient

ApexiCon® E, Psorcon E®Δ

0.05

Yes

Desoximetasone

Ointment

Topicort®

0.25

Yes

Cream

Topicort®

0.25

Yes

Gel

Topicort®

0.05

Yes

Triamcinolone acetonide

Ointment

Kenalog®Δ

0.5

Yes

High potency (group three)

Amcinonide

Cream

Cyclocort®, Amcort®Δ

0.1

Yes

Lotion

Amcort®Δ

0.1

Yes

Betamethasone dipropionate

Cream, hydrophilic emollient

Diprosone®

0.05

Yes

Lotion

Diprosone®

0.05

Yes

Betamethasone valerate

Ointment

Valisone®Δ, Betatrex®Δ

0.1

Yes

Foam

Luxiq®

0.12

No

Fluticasone propionate

Ointment

Cutivate®

0.005

Yes

Fluocinonide

Cream aqueous emollient

Lidex-E®

0.05

No

Mometasone furoate

Ointment

Elocon®

0.1

Yes

Desoximetasone

Cream

Topicort LP®

0.05

Yes

Diflorasone diacetate

Cream

Maxiflor®Δ, Florone®Δ, Psorcon®Δ

0.05

Yes

Triamcinolone acetonide

Ointment

Kenalog ®Δ

0.5

Yes

Cream

Aristocort HP®Δ

0.5

Yes

Ointment

Aristocort A®Δ

0.1

Yes

Medium potency (group four)

         

Triamcinolone acetonide

Cream

Kenalog®Δ, Kenonel®

0.1

Yes

Ointment

Kenalog®Δ

0.1

Yes

Aerosol spray

Kenalog®

0.2 mg per 2 second spray

No

Flurandrenolide

Ointment

Cordran®

0.05

No

Fluocinolone acetonide

Ointment

Synalar®

0.025

Yes

Mometasone furoate

Cream

Elocon®, Momexin®

0.1

Yes

Lotion

Elocon®

0.1

Yes

Solution

Elocon®Δ

0.1

Yes

Hydrocortisone valerate

Ointment

Westcort®

0.2

Yes

Clocortolone pivalate

Cream

Cloderm®

0.1

No

LIST CONTINUED IN TABLE "TOPICAL GLUCOCORTICOIDS II".

* Listed by potency: group one is the most potent, group seven is the least potent.
• Vehicle and base ingredient(s) for generic products, in some cases, may not be identical to trade version.
Δ Inactive US trade name for specific product; brand may be available outside US.

Data from: Lacy, CF et al (Eds) Lexi-Comp's Drug Information Handbook, 18th ed. Lexi-Comp Inc, Hudson OH. Copyright © 2010 and Tadicherla, S, Ross, K, Shenefelt, D, Topical corticosteroids in dermatology; Journal of Drugs in Dermatology 2009; 12:1093.

Comparison of representative topical corticosteroid preparations, continued

Potency group*

Corticosteroid

Vehicle type/form

Trade names (US)

Available strength(s), percent (except as noted)

Generic available in US•

Lower-mid potency (group five)

Triamcinolone acetonide

Lotion

Kenalog®Δ

0.1

Yes

Ointment

Kenalog®Δ

0.025

Yes

Betamethasone dipropionate

Lotion

Diprosone®

0.05

Yes

Flurandrenolide

Cream

Cordran®

0.05

No

Lotion

Cordran®

0.05

No

Fluticasone propionate

Cream

Cutivate®

0.05

Yes

Lotion

Cutivate®

0.05

No

Prednicarbate

Cream, emollient

Dermatop®

0.1

Yes

Ointment

Dermatop®

0.1

Yes

Desonide

Ointment

DesOwen®, Tridesilon®Δ

0.05

Yes

Gel

Desonate®

0.05

No

Betamethasone valerate

Cream

Beta-Val®, Betatrex®Δ, Valisone®Δ

0.1

Yes

Hydrocortisone valerate

Cream

Westcort®

0.2

Yes

Hydrocortisone butyrate

Ointment

Locoid®

0.1

Yes

Cream

Locoid®, Locoid Lipocream®

0.1

Yes

Lotion, spray

Cortizone10® maximum

0.1

No

Solution

Locoid®

0.1

Yes

Hydrocortisone probutate

Cream

Pandel®

0.1

No

Fluocinolone acetonide

Cream

Synalar®

0.025

Yes

Low potency (group six)

Alclometasone dipropionate

Ointment

Aclovate®

0.05

Yes

Cream

Aclovate®

0.05

Yes

Triamcinolone acetonide

Cream

Kenalog®Δ, Aristocort®Δ

0.025

Yes

Lotion

Kenalog®Δ

0.025

Yes

Desonide

Cream

DesOwen® , Tridesilon®Δ

0.05

Yes

Lotion

DesOwen®, LoKara®

0.05

Yes

Foam

Verdeso®

0.05

No

Betamethasone valerate

Lotion

Beta-Val®, Valisone®Δ

0.1

Yes

Fluocinolone acetonide

Cream

Synalar®

0.01

Yes

Solution

Synalar®

0.01

Yes

Shampoo

Capex®

0.01

No

Oil (scalp)

Derma-Smoothe/FS®

0.01

No

Oil (body)

Derma-Smoothe/FS®

0.01

No

Least potent (group seven)

Hydrocortisone (base)

Ointment

Hytone®

2.5

Yes

Cream

Hytone®, Nutracort®

2.5

Yes

Lotion

Hytone®

2.5

Yes

Solution

Texacort®

2.5

Yes

Hydrocortisone acetate with pramoxine 1 percent combination

Ointment

Pramosone®

1

Yes

Cream

Pramosone®, Analpram HC

1

Yes

Lotion

Cortane B Lotion®

1

Yes

Aerosol foam

Epifoam®

1

Yes

Hydrocortisone (base)

Ointment

Cortaid®, Hytone®, Nutracort®

1

Yes

Cream

Cortaid®, Hytone®, Synacort

1

Yes

Lotion

Cetacort®, Hytone®, Nutracort®

1

Yes

Spray

Cortaid®

1

Yes

Ointment

Lanacort-5®, Cortaid®

0.5

Yes

Cream

Lanacort-5®, Cortaid®

0.5

Yes

THIS TABLE IS A CONTINUATION OF TABLE "TOPICAL GLUCOCORTICOIDS I".

* Listed by potency: group one is the most potent, group seven is the least potent.
• Vehicle and base ingredient(s) for generic products, in some cases, may not be identical to trade version.
Δ Inactive US trade name for specific product; brand may be available outside US.
48 percent refined peanut oil.

Data from: Lacy, CF et al (Eds) Lexi-Comp's Drug Information Handbook, 18th ed. Lexi-Comp Inc, Hudson OH. Copyright © 2010 and Tadicherla, S, Ross, K, Shenefelt, D, Topical corticosteroids in dermatology; Journal of Drugs in Dermatology 2009;12:1093.

 其他資料:

認識皮質類固醇 

外用類固醇 class 分級比較表(1~7) 

類固醇 比較表格 http://mulicia.pixnet.net/blog/post/4935795

類固醇劑量轉換 corticosteroid converter http://mulicia.pixnet.net/blog/post/18790616

Topical Corticosteroids (By HFS) http://mulicia.pixnet.net/blog/post/18792156

Comparison of Glucocorticoid potency http://mulicia.pixnet.net/blog/post/18652923

Relative potency of selected corticosteroid products http://mulicia.pixnet.net/blog/post/4936645

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